Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLAU All Species: 6.36
Human Site: Y304 Identified Species: 15.56
UniProt: P00749 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00749 NP_001138503.1 431 48507 Y304 T I C L P S M Y N D P Q F G T
Chimpanzee Pan troglodytes XP_528120 687 76517 D560 T V C L P P A D L Q L P D W T
Rhesus Macaque Macaca mulatta XP_001099358 430 48241 Y303 T I C L P S T Y N D P P F G T
Dog Lupus familis XP_536394 543 59426 R416 T I C L P P S R G D A H F G A
Cat Felis silvestris
Mouse Mus musculus P06869 433 48249 F306 T I C L P P R F T D A P F G S
Rat Rattus norvegicus P29598 432 47939 F305 T I C L P P R F G D A P F G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510562 432 48862 S298 T I C L P T S S R D P P S Y A
Chicken Gallus gallus P15120 434 49381 N301 T V C L P E K N L N L Y D N T
Frog Xenopus laevis NP_001083592 553 62071 E426 P A C F P D S E M T L P D W T
Zebra Danio Brachydanio rerio XP_001346717 292 32083 P166 K T V C I P G P N V S L S D G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 30.1 93 61.8 N.A. 69 71.3 N.A. 55.5 46.5 35.4 31 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 41 96.9 69.2 N.A. 81.9 83 N.A. 68.7 62.6 45.3 43.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 33.3 86.6 53.3 N.A. 53.3 53.3 N.A. 46.6 33.3 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 40 86.6 53.3 N.A. 66.6 66.6 N.A. 53.3 46.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 0 0 10 0 0 0 30 0 0 0 20 % A
% Cys: 0 0 90 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 10 0 60 0 0 30 10 0 % D
% Glu: 0 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 20 0 0 0 0 50 0 0 % F
% Gly: 0 0 0 0 0 0 10 0 20 0 0 0 0 50 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % H
% Ile: 0 60 0 0 10 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 80 0 0 0 0 20 0 30 10 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 10 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 30 10 0 0 0 10 0 % N
% Pro: 10 0 0 0 90 50 0 10 0 0 30 60 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % Q
% Arg: 0 0 0 0 0 0 20 10 10 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 20 30 10 0 0 10 0 20 0 20 % S
% Thr: 80 10 0 0 0 10 10 0 10 10 0 0 0 0 50 % T
% Val: 0 20 10 0 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % W
% Tyr: 0 0 0 0 0 0 0 20 0 0 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _